Critical congenital heart defects are usually defined as structural malformations of the heart that are present at birth and require intervention in the 1st year of life.[1] Congenital heart disease has been reported to be responsible for 30–50% of infant mortality due to birth defects.[2] During the period from 1999 to 2006 (before the advent of critical congenital heart disease [CCHD] newborn screening), more than 13,000 infant deaths caused by congenital heart defects were reported in the United States.[